Topical 2% tofacitinib for children with alopecia areata, alopecia totalis, and alopecia universalis
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چکیده
منابع مشابه
Transient Efficacy of Tofacitinib in Alopecia Areata Universalis
Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, ...
متن کاملTopical and intralesional therapies for alopecia areata.
Alopecia areata is a common form of nonscarring alopecia. It affects males and females equally and has no racial predilection. It usually affects the scalp, but any hair-bearing area can be involved. It presents as patchy hair loss, loss of hair on the entire scalp (alopecia totalis), or the whole body (alopecia universalis). The histopathology varies according to the disease stage, but usually...
متن کاملTopical dinitrochlorobenzene (DNCB) for alopecia areata: Revisited.
1. Rapp SR, Feldman SR, Exum ML, Fleischer AB Jr, Reboussin DM. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 1999;41:401-7. 2. Reed WB, Becker SW, Rhode, Heiskell CL. Psoriasis and arthritis: A clinicopathological study. Arch Dermatol 1961;83:541-8. 3. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in pat...
متن کاملAlopecia areata.
n engl j med 367;3 nejm.org july 19, 2012 279 methacin should be used in addition to pancre atic stents in highrisk patients. However, post hoc analysis of our trial suggests that indometha cin may obviate the need for prophylactic pan creatic stent placement (unpublished data), and we therefore agree with Baron et al. that com parative effectiveness studies of indomethacin and pancreatic ...
متن کاملClinical Characteristics and Prognostic Factors in Early-Onset Alopecia Totalis and Alopecia Universalis
Alopecia totalis (AT) and alopecia universalis (AU), severe forms of alopecia areata (AA), show distinguishable clinical characteristics from those of patch AA. In this study, we investigated the clinical characteristics of AT/AU according to the onset age. Based on the onset age around adolescence (< or ≥ 13 yr), 108 patients were classified in an early-onset group and the other 179 patients i...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 2018
ISSN: 0190-9622
DOI: 10.1016/j.jaad.2018.02.031